- Title
- Trisphaerolide A, a novel polyketide from the Dominican sponge Erylus trisphaerus
- Creator
- van Altena , Ian; van Soest , Rob; Roberge, Michel; Andersen, Raymond J.
- Relation
- Journal of Natural Products Vol. 66, Issue 4, p. 561-563
- Publisher Link
- http://dx.doi.org/10.1021/np0205147
- Publisher
- American Chemical Society
- Resource Type
- journal article
- Date
- 2003
- Description
- The structure of trisphaerolide A (1), a mildly cytotoxic metabolite isolated from extracts of the marine sponge Erylus trisphaerus collected in Dominica, has been elucidated by detailed analysis of spectroscopic data. Trisphaerolide A (1) has a putative polyketide biogenesis, incorporating a rare variant on the standard pathway, which involves the addition of methyl branches arising from C-2 carbons of acetate units to chain carbons that arise from C-1 of acetate units.
- Subject
- trisphaerolide A; Erylus trisphaerus; polyketide
- Identifier
- uon:1804
- Identifier
- http://hdl.handle.net/1959.13/27570
- Identifier
- ISSN:0163-3864
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